Violence ravages the Windy City as 48 people are shot with 7 dead.

A 5-year-old girl was stabbed to death Saturday morning in Chicago during another bloody weekend in the city that also resulted in at least 49 people being shot, including seven fatally, reports say.

The girl, identified as Serenity Arrington, suffered multiple stab wounds and died shortly after being rushed to a local hospital, according to CBS Chicago. Neighbors in East Garfield Park tried to assist the girl, while her mother, 27-year-old Simone Austin, was charged in her death with first-degree murder, the report added. The motive for the attack was not immediately clear.

Police have also launched a homicide investigation after the body of a woman with multiple stab wounds to her face and neck was retrieved Sunday morning from the Chicago River, the Chicago Sun-Times reports. That woman appeared to be in her mid-20s.

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The weekend's gun violence in the city began Friday night when a 19-year-old man reportedly was shot in the back and chest while walking in an alley. He later was pronounced dead at a local hospital.

The next morning, a 17-year-old reportedly was standing in an alley in a different part of the city and was approached by two men. He was shot in the upper torso at about 11:10 a.m. and pronounced dead at the scene, NBC Chicago reported.

In other shootings targeting teenagers, a 17-year-old male was critically wounded in a drive-by attack in Englewood Sunday morning, while a 15-year-old male was struck in the leg after being approached by a vehicle later that day in the South Shore, police told the Chicago Sun-Times.

On Sunday night, a 20-year-old was reported to have died after being dropped off at a hospital in Englewood with a gunshot wound to his head.

A 42-year-old man also died after being shot in the back at a gathering early Saturday in the South Shore, according to the Chicago Sun-Times.

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The newspaper says the ages of those who died in the weekend shootings were males ranging from 15 to 66 years old.

Last weekend, there were 10 killed and 35 injured by gun violence in Chicago, it added.